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Rhodopsin Information

Rhodopsin is expressed in vertebrate photoreceptor cells. It is a pigment of the retina that is responsible for both the formation of the photoreceptor cells and the first events in the perception of light. Retinal is the light absorbing pigment molecule and is a derivative of vitamin A. Rhodopsin consists of two building blocks, an opsin protein called scotopsin and a reversibly covalently bound cofactor, retinal. Rhodopsins (visual purple) belong to the class of G-protein coupled receptors. It is the chemical that allows night-vision, and is extremely sensitive to light. Rhodopsin consists of the protein opsin linked to 11-cis retinal a prosthetic group. Rhodopsin of the rods most strongly absorbs green-blue light and therefore appears reddish-purple, which is why it is also called "visual purple". It is responsible for the monochromatic vision in the dark. Rhodopsin is made in the rod inner segment and is transported from there to the ROS on small membrane spheres called vesicles. Rhodopsin is a transmembrane protein consisting of 7 membrane-spanning helices, that are interconnected by extracellular and cytoplasmic loops. Humans cannot make Rhodopsin, instead they use and external source, b -carotene, that is found in food in order to synthesis it.

Symptoms of Rhodopsin

Some sign and symptoms related to Rhodopsin are as follows:

  • Constipitation.
  • Fever.
  • Malnutrition
  • Othere vitamin deficiency.
  • Infection.


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